diff --git a/README.md b/README.md index b3e7dae..8434253 100644 --- a/README.md +++ b/README.md @@ -1,62 +1,21 @@ # LiaoWJLab -## About Us +LiaoWJLab builds bioinformatics and machine-learning tools for immuno-oncology and precision oncology, focusing on predicting cancer immunotherapy responses. -LiaoWJLab specializes in immuno-oncology and precision oncology research. We are dedicated to developing innovative tumor immunotherapy prediction tools using bioinformatics and machine learning methods. +## Projects +- 🧬 TMEclassifier — Tumor microenvironment subtype classifier (R) +- 🫁 LIRA — Lung cancer immunotherapy response predictor (R) +- 📊 IKCscore — Immunotherapy scoring for NSCLC (R) +- 🔬 scsig — Single-cell differential feature package (R) +- 🧪 uaiscore — Urothelial carcinoma immunotherapy stratification (R) +- 🧬 FBI — Fusion Burden Index pipeline (Shell, in progress) -## Main Projects - -### Open-source Projects - -#### 🧬 [TMEclassifier](https://github.com/LiaoWJLab/TMEclassifier) -An ensemble machine learning–based tumor microenvironment subtype classifier -- Language: R -- Applications: gastric cancer, immunotherapy, tumor microenvironment analysis -- ⭐ Stars: 7 - -#### 🫁 [LIRA](https://github.com/LiaoWJLab/LIRA) -AI model for predicting lung cancer immunotherapy response -- Language: R -- Applications: lung cancer immunotherapy response prediction -- ⭐ Stars: 3 - -#### 📊 [IKCscore](https://github.com/LiaoWJLab/IKCscore) -Immunotherapy prediction scoring system for non–small cell lung cancer -- Language: R -- Applications: non–small cell lung cancer immunotherapy prediction -- ⭐ Stars: 2 - -#### 🔬 [scsig](https://github.com/LiaoWJLab/scsig) -Single-cell differential feature identification package -- Language: R -- Applications: single-cell sequencing data analysis -- ⭐ Stars: 2 - -#### 🧪 [uaiscore](https://github.com/LiaoWJLab/uaiscore) -Adjuvant immunotherapy stratification tool for urothelial carcinoma -- Language: R -- Applications: urothelial carcinoma immunotherapy stratification - -### In Progress - -#### 🧬 [FBI](https://github.com/LiaoWJLab/FBI) -Fusion Burden Index analysis pipeline -- Language: Shell -- Status: Last updated on 2025-11-15 - -## Research Focus - -Our research primarily focuses on: -- 🎯 Predicting responses to cancer immunotherapy -- 🔬 Tumor microenvironment analysis -- 🧬 Single-cell sequencing data analysis -- 🤖 Applying machine learning to precision oncology -- 📊 Developing bioinformatics tools +## Focus +- Predicting immunotherapy response +- Tumor microenvironment and single-cell analysis +- Machine learning for precision oncology ## License +MIT -The open-source projects under this organization are licensed under the MIT License. - ---- - -**LiaoWJLab** — Focused on Immuno-Oncology and Precision Oncology +**LiaoWJLab** — Immuno-Oncology & Precision Oncology